Nitrogen mustard compounds
Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 50 MG
HN37 is a potent and chemically stable antiepileptic agent candidate with an EC50 of 37 nM for KCNQ2. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In vitro, HN37 is a potent neuronal Kv7 activator with subtype selectivity similar to RTG.
- Potent and chemically stable antiepileptic agent candidate
- EC50 of 37 nM for KCNQ2
- Click chemistry reagent with an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Potent neuronal Kv7 activator with subtype selectivity similar to RTG
Medchemexpress LLC 1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 56239-24-8 | 99.0% | C9H12D4ClN3O3 | 1 MG
trans-4'-Hydroxy CCNU Lomustine-d4 is a deuterium-labeled compound, primarily used as a tracer or as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes, like deuterium, into drug molecules serves as a critical method for quantitation during drug development, with the potential to influence pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs.
Aobchem 1-(1-Chloroethyl)-2-fluorobenzene | 95% | CAS 60907-87-1 | C8H8ClF | 1g
1-(1-Chloroethyl)-2-fluorobenzene | 95% | CAS 60907-87-1 | C8H8ClF | 1g
eMolecules 1122-96-9 | AstaTech | 4-METHOXYPYRIDINE 1-OXIDE | 5g | 233625492 | 34702 | 95 | MFCD00006207 | 125.127 | C6H7NO2
Medchem Express | Delta-Tocopherol | 50mg | 482204049 | HY-113026 | 119-13-1 | MFCD20486794 | 402.663 | C27H46O2
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![Medchemexpress LLC 5-amino-N-(3-fluoro-4-methoxybenzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide | 1451994-10-7 | 99.3% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234776.png-250.jpg)
Medchemexpress LLC 5-amino-N-(3-fluoro-4-methoxybenzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide | 1451994-10-7 | 99.3% | 50 MG
VU0467485 (AZ13713945) is a potent, selective, orally bioavailable positive allosteric modulator of the muscarinic acetylcholine receptor M4, provided as a research reagent for receptor pharmacology and preclinical studies.
- Potent and selective M4 positive allosteric modulator.
- Orally bioavailable properties support in vivo evaluation.
- High purity suitable for pharmacological assays.
- Available in multiple pack sizes, including 50 mg.
- Commonly used for studies of M4 signaling and antipsychotic-like activity in preclinical models.
eMolecules 19685-10-0 | Medchem Express | 10-Methoxycamptothecin | 5mg | 532150217 | HY-N0446 | MFCD11975376 | 378.384 | C21H18N2O5
Ambeed | (2S5S)-Hexane-25-diol | 250mg | 562292693 | A447376 | 34338-96-0 | MFCD00082583 | 118.176 | C6H14O2
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Medchemexpress LLC Mizagliflozin | 666843-10-3 | 99.2% | 564.67 | 5 MG
Mizagliflozin (DSP-3235 free base) is a potent, orally active, and selective SGLT1 inhibitor with a Ki of 27 nM for human SGLT1. It shows 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. It also exhibits potential in the amelioration of chronic constipation.
- Potent, orally active, and selective SGLT1 inhibitor (Ki of 27 nM for human SGLT1)
- 303-fold selectivity over SGLT2
- Solid appearance, off-white to light yellow color
- Used as an antidiabetic agent to modify postprandial blood glucose excursion
- Exhibits potential in the amelioration of chronic constipation
Medchemexpress LLC Bis(2-chloroethyl)amine hydrochloride | 821-48-7 | MFCD00012515 | 98.0% | 178.49 | C4H10Cl3N | 1kg
Bis(2-chloroethyl)amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC ML-184 10mg | 794572-10-4 | 470.63 g·mol⁻¹ | C25H34N4O3S | 10 MG
ML-184 is a selective GPR55 agonist research compound supplied for in vitro and preclinical pharmacology studies. It is provided as a solid and as ready-to-use DMSO solutions, and is characterized by molecular formula C25H34N4O3S and molecular weight 470.63 g·mol⁻¹.
- Selective GPR55 agonist (EC50 ≈ 250 nM)
- Suitable for in vitro and preclinical research applications
- Available as a 10 mg solid and as 10 mM solution in DMSO
- High purity (99.57%) as provided by manufacturer
- Store powder at -20°C for long-term stability; store solutions at -80°C for extended storage
Medchemexpress LLC Cdc25b-in-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 10MG
CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase, referred to in the literature as compound 4a. It is provided as a 10 mg research sample (CAS 2374831-10-2) for biochemical and cellular studies targeting CDC25B-mediated signaling.
- Potent CDC25B inhibition with reported Ki of 8.5 μM.
- High purity suitable for research (≈98.1%).
- Molecular weight 321.37 g/mol; formula C20H19NO3.
- Suitable for in vitro biochemical and cell-based assays.
- Storage under nitrogen recommended; refrigerated at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
- Supplied as a small quantity research sample for laboratory use.
eMolecules 1523618-10-1 | ChemScene | 4-(Cyclopropylsulfonimidoyl)aniline | 100mg | 761283903 | CS-0184344 | MFCD27987215 | 196.27 | C9H12N2OS
Medchem Express | -Lactamase-IN-2 | 5mg | 582658792 | HY-138247 | 2114651-20-4 | 208.188 | C11H9FO3
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Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 100 MG
HN37 is a potent and chemically stable antiepileptic agent candidate, demonstrating an EC50 of 37 nM for KCNQ2. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. It is also recognized as a potent neuronal Kv7 activator, exhibiting subtype selectivity similar to RTG.
- Potent and chemically stable antiepileptic agent candidate
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Potent neuronal Kv7 activator
- Exhibits subtype selectivity similar to RTG
- Molecular weight of 340.39
- Appears as an off-white to light yellow solid
- Intended for research use only
![STA Pharmaceutical 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 5 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502344475.PNG-250.jpg)
STA Pharmaceutical 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 5 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N
3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O
Medchemexpress LLC Camonsertib | 2417489-10-0 | MFCD34578462 | 100.0% | C21H26N6O3 | 10MG
Camonsertib is an orally active, selective ATR kinase inhibitor developed for oncology research and clinical investigation. It exhibits low-nanomolar biochemical potency against ATR, reported selectivity versus related kinases, and has shown antitumor activity in preclinical and early clinical studies. The compound is supplied as a high-purity solid for research use only.
- Potent ATR inhibition with low-nanomolar biochemical potency.
- High selectivity versus related kinases, limiting off-target effects.
- Demonstrated antitumor activity in preclinical and early clinical evaluations.
- Provided as a high-purity solid suitable for laboratory research.
- Available in small research-scale quantities for experimental studies.